CDK2-IN-4
CAS No. : 2079895-42-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $98 | In-stock |
| 5mg | $260 | In-stock |
| 10mg | $410 | In-stock |
| 25mg | $700 | In-stock |
| 50mg | $980 | In-stock |
| 100mg | $1370 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-117535 |
| M.Wt: | 442.49 |
| Formula: | C23H18N6O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 20.83 mg/mL (ultrasonic) |
CDK2-IN-4 (compound 73) is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)[1]. IC50 & Target:IC50: 44 nM (CDK2/cyclin A), 86 μM (CDK1/cyclin B)[1] In Vitro:CDK2-IN-4 (compound 73) demonstrates appreciable nanomolar potency versus CDK2 in isolated kinase assays, the maximal concentration tested in cellular assays (30 μM) had no or limited effects on the growth of cells[1]
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