RS-601
CAS No. : 207987-59-5
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| 5mg | $3465 | Get quote |
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| Cat. No. : | HY-U00072 |
| M.Wt: | 511.48 |
| Formula: | C22H23F6NO4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities. In Vivo: RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR[1].
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