BB-78485


CAS No. : 207732-11-4

207732-11-4
Price and Availability of CAS No. : 207732-11-4
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Cat. No. : HY-121021
M.Wt: 420.48
Formula: C23H20N2O4S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 207732-11-4 :

BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1].
IC50 & Target:IC50: 160 nM(LpxC)[1] In Vitro:BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].
BB-78485 has effect against D21 and D22 (lpxC101) with MICs values of 2 μg/mL and 0.016 μg/mL, respectively[1].
BB-78485 shows predominantly gram-negative activities against members of the Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia with MICs values range from 1μg/mL to 32 μg/mL[1].

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