IWP-O1
CAS No. : 2074607-48-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $125 | In-stock |
| 25mg | $200 | In-stock |
| 50mg | $286 | In-stock |
| 100mg | $405 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100853 |
| M.Wt: | 432.48 |
| Formula: | C26H20N6O |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells[1]. IC50 & Target: EC50: 80 pM (Porcn)[1]. In Vitro: IWP-O1 (17) suppresses Wnt signaling in L-Wnt-STF cells with an EC50 value of 80 pM, 2.5 times more active than the investigational drug LGK974[1].
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