TB-21007
CAS No. : 207306-50-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-103510 |
| M.Wt: | 339.50 |
| Formula: | C15H17NO2S3 |
| Purity: | >98 % |
| Solubility: | DMSO : 40 mg/mL (ultrasonic;warming) |
TB-21007 is a selective and brain penetrant α5 subunit-containing GABAA receptor inverse agonist with Kis of 1.6 nM, 20 nM, 16 nM, and 20 nM for α5, α1, α2 and α3 subtypes, respectively. TB-21007 enhances cognition in rats[1]. In Vivo:TB-21007 (compound 43) (0.3 mg/kg; ip; for 5 days) enhances cognitive performance in rats in the delayed 'matching-to-place' Morris water maze test-a hippocampal-dependent memory task[1].
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