WEHI-539 hydrochloride
CAS No. : 2070018-33-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $112 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $500 | In-stock |
| 100mg | $775 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15607A |
| M.Wt: | 620.18 |
| Formula: | C31H30ClN5O3S2 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 16.67 mg/mL (ultrasonic) |
WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM. IC50 & Target:IC50: 1.1 nM (Bcl-XL)[1] In Vitro: WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells[2].
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