(S)-C33
CAS No. : 2066488-39-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $190 | In-stock |
| 50mg | $280 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-124775 |
| M.Wt: | 357.84 |
| Formula: | C18H20ClN5O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
(S)-C33 is a potent and selective PDE9 (phosphodiesterase-9) inhibitor, with an IC50 of 11 nM. (S)-C33 can be used for central nervous system diseases and diabetes research[1]. IC50 & Target:IC50: 11 ± 4 nM (PDE9A), 366 ± 38 nM (PDE5A1), 554 ± 64 nM (PDE1B2), 1.0 ± 0.2 μM (PDE8A1), 1.3 ± 0.1 μM (PDE4D2), 2.3 ± 0.3 μM (PDE10A1), 2.4 ± 0.5 μM (PDE2A3), 2.5 ± 0.5 μM (PDE7A1)[1] In Vitro:(S)-C33 shows the T1/2 values of 105 and 54 minutes in human and mouse microsomes[1].
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