Pasiniazid


CAS No. : 2066-89-9

(Synonyms: Paraniazide; Pasiniazide; Isonicotinic acid hydrazide p-aminosalicylate)

2066-89-9
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Cat. No. : HY-B1048
M.Wt: 290.27
Formula: C13H14N4O4
Purity: >98 %
Solubility: DMSO : ≥ 160 mg/mL
Introduction of 2066-89-9 :

Pasiniazid is a chemical complex formed by Isoniazid (HY-B0329) and Para-aminosalicylic acid in a 1:1 molar ratio. Pasiniazid is an antibacterial agent. Pasiniazid is rapidly decomposed into isoniazid and para-aminosalicylic acid in the gastrointestinal tract. Isoniazid exerts a bactericidal effect, while para-aminosalicylic acid delays the acetylation process of isoniazid. Pasiniazid has antibacterial activity against Mycobacterium tuberculosis. Pasiniazid can be used in tuberculosis research[1]. In Vitro:Pasiniazid (0.125-256 μg/mL) shows that 85 out of 109 INH-resistant Mycobacterium tuberculosis isolates are susceptible to it[1].

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