Calycosin-7-O-β-D-glucoside


CAS No. : 20633-67-4

(Synonyms: Calycosin-7-glucoside)

20633-67-4
Price and Availability of CAS No. : 20633-67-4
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Cat. No. : HY-N0520
M.Wt: 446.40
Formula: C22H22O10
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 20633-67-4 :

Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects[1][2]. In Vitro: Calycosin-7-O-β-D-glucoside (2 μM; 6 hours) remarkably inhibits the expression and activities of MMPs, and secures the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex[1]. In Vivo: Calycosin-7-O-β-D-glucoside (intraperitoneal injection; 26.8 mg/kg; 14 days) significantly reduces infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia-reperfusion rat model[1].

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