MS-PPOH


CAS No. : 206052-02-0

206052-02-0
Price and Availability of CAS No. : 206052-02-0
Size Price Stock
5mg $80 In-stock
10mg $128 In-stock
25mg $256 In-stock
50mg $410 In-stock
100mg $656 In-stock
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Cat. No. : HY-114759
M.Wt: 323.41
Formula: C16H21NO4S
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 206052-02-0 :

MS-PPOH is a potent and selective cytochrome P450 (CYP) epoxygenase inhibitor[1]. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 μM, respectively[2]. MS-PPOH is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: MS-PPOH blocks cellular EET synthesis. MS-PPOH inhibits tonic (basal) cell invasion and migration and reduces the 11,12-EET (1.0 μM)-induced cell motility[1]. In Vivo: MS-PPOH (20 mg/kg/day, i.v.) for 6 days significantly reduced renal levels of epoxyeicosatrienoic acids (EETs) in Dahl salt-resistant rats on 2% NaCl drinking solution[3].

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