PPOH
CAS No. : 206052-01-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $145 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $485 | In-stock |
| 100mg | $780 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-119647 |
| M.Wt: | 246.30 |
| Formula: | C15H18O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively[1].
In Vitro:PPOH (5 μM) can inhibit CYP2C9 activity by 63 and 90%, respectively, in the absence and presence of the 30-min NADPH preincubation and 63% when the 30-min preincubation omitted NADPH[1].
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