CCG 258001
CAS No. : 2055990-96-8
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| Cat. No. : | HY-120168 |
| M.Wt: | 339.41 |
| Formula: | C20H22FN3O |
| Purity: | >98 % |
| Solubility: |
CCG 258001 is a GRK inhibitor with IC50 values of 0.29, 51.8, and 33 µM against GRK2, GRK1, and GRK5, respectively. CCG 258001 inhibits GRK activity in cardiomyocytes and other muscle cells. CCG 258001 is applicable to the research of heart diseases, including heart failure, myocardial hypertrophy, and hypertension[1]. In Vitro:CCG 258001 (5 min) potently inhibits GRK2 with an IC50 of 0.29 µM, while it shows weak inhibitory effects on GRK1 and GRK5[1].
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