SR12343
CAS No. : 2055101-86-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $165 | In-stock |
| 10mg | $260 | In-stock |
| 25mg | $570 | In-stock |
| 50mg | $912 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-123936 |
| M.Wt: | 368.66 |
| Formula: | C15H15BrClN3O |
| Purity: | >98 % |
| Solubility: |
SR12343, an IKK/NF-κB inhibitor, is a NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic. SR12343 inhibits TNF-α- and LPS-induced NF-κB activation by blocking the interaction between IKKβ and NEMO, with an IC50 of 37.02 μM for TNF-α-mediated NF-κB activation. SR12343 suppresses LPS-induced acute pulmonary inflammation in mice. SR12343 can be used for research of inflammatory and degenerative diseases[1].
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