GLPG2451
CAS No. : 2055015-61-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $315 | In-stock |
| 10mg | $495 | In-stock |
| 25mg | $990 | In-stock |
| 50mg | $1480 | In-stock |
| 100mg | $1980 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-119936 |
| M.Wt: | 419.38 |
| Formula: | C16H16F3N3O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1]. IC50 & Target: Cystic fibrosis transmembrane conductance regulator[1] In Vitro: GLPG2451 has an EC50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells[1].
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