Tubulysin B
CAS No. : 205304-87-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $700 | In-stock |
| 5mg | $1750 | In-stock |
| 10mg | $2800 | In-stock |
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| Cat. No. : | HY-N1243 |
| M.Wt: | 830.04 |
| Formula: | C42H63N5O10S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Tubulysin B is a highly cytotoxic peptide and potent microtubule destabilizing agents isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin B has IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties[1].Tubulysin B is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[2]. In Vitro: Tubulysin B has IC50s of 0.6 and 0.9 nM against KB and A549 tumors cell lines, respectively.
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