IDN-1965
CAS No. : 204919-14-2
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| Cat. No. : | HY-120257 |
| M.Wt: | 419.45 |
| Formula: | C21H26FN3O5 |
| Purity: | >98 % |
| Solubility: |
IDN-1965 is an irreversible, broad-spectrum caspase inhibitor. IDN-1965 prevents downstream apoptotic events (such as DNase activation) and significantly delays cytochrome c release by inhibiting caspase activity. IDN-1965 significantly delayed death in mice with cardiomyocyte apoptosis. IDN-1965 completely prevents left ventricular dilation, systolic dysfunction, and fibrosis in mice with dilated cardiomyopathy. IDN-1965 can be used to study apoptosis-related diseases such as heart failure and the mechanisms of apoptosis initiation[1][2].
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- IDN-1965
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