RTI 336


CAS No. : 204069-50-1

204069-50-1
Price and Availability of CAS No. : 204069-50-1
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Cat. No. : HY-107055
M.Wt: 429.38
Formula: C24H26Cl2N2O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 204069-50-1 :

RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. RTI 336 inhibits addictive agent induced locomotor activity and self-administration in Lewis rats. RTI 336 exhibits inhibitory effects depending on inherent NAc DAT levels[1]. In Vivo:RTI 336 (3 mg/kg; sc; 30 min pretreatment) significantly decreases the number of infusions of addictive agent in Lewis rats[1].
RTI 336 (3 mg/kg; ip; 30 min pretreatment) decreases response rates (lever presses/s) induced by addictive agent in Lewis rats[1].

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