BI-6901


CAS No. : 2040401-92-9

2040401-92-9
Price and Availability of CAS No. : 2040401-92-9
Size Price Stock
5mg $380 In-stock
10mg $600 In-stock
25mg $1150 In-stock
50mg $1800 In-stock
100mg $2850 In-stock
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500 mg Get quote
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Cat. No. : HY-116835
M.Wt: 453.56
Formula: C23H27N5O3S
Purity: >98 %
Solubility: DMSO : 160 mg/mL (ultrasonic)
Introduction of 2040401-92-9 :

BI 6901 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research[1]. In Vivo: BI-6901 (intraperitoneal injection; 100 mg/kg; bid.) exhibits a dose-dependent anti-inflammatory response against DNFB stimulated ear swelling in sensitized mice. The level of efficacy observed for BI-6901 is similar to that observed with anti-CCL27 antibody in the same model (60-85%)[1].

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