Arctiin


CAS No. : 20362-31-6

(Synonyms: Arctii; NSC 315527; Arctigenin-4-glucoside)

20362-31-6
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Cat. No. : HY-N0034
M.Wt: 534.55
Formula: C27H34O11
Purity: >98 %
Solubility: H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 250 mg/mL (ultrasonic)
Introduction of 20362-31-6 :

Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in ammatory cytokines levels. Arctiin can used in study glomerulonephritis[4][6]. In Vitro: Arctiin (100 μM) down-regulates cyclin D1 protein expression in human tumor cells[6]. In Vivo: Arctiin (120 mg/kg for p.o.;Once daily for 3 weeks) significantly improves cBSA-induced glomerulonephritis in glomerulonephritis rat model[4].

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