Laninamivir octanoate


CAS No. : 203120-46-1

(Synonyms: CS-8958)

203120-46-1
Price and Availability of CAS No. : 203120-46-1
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Cat. No. : HY-14818A
M.Wt: 472.53
Formula: C21H36N4O8
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 203120-46-1 :

Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses[1][2]. In Vitro: Laninamivir octanoate (CS-8958) shows inhibitory activity with an IC50 of 631-1170 nM, 39.2-221 nM and 128 nM to the H1N1 viruses strains, H3N2 viruses strains and H2N2 (A/Singapore/1/57) virus, respectively[1]. In Vivo: Laninamivir octanoate (CS-8958; 95 μg/kg; intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection) treatment shows significantly life-prolonging effect in infected model[1].

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