Laninamivir
CAS No. : 203120-17-6
(Synonyms: R 125489)
| Size | Price | Stock |
|---|---|---|
| 5mg | $96 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $250 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14818 |
| M.Wt: | 346.34 |
| Formula: | C13H22N4O7 |
| Purity: | >98 % |
| Solubility: | H2O : 5 mg/mL (ultrasonic) |
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively[1].
IC50 & Target:IC50: 0.90 nM (N5), 1.83 nM (p09N1), 3.12 nM (p57N2)[1]
In Vitro: Laninamivir (R 125489) inhibits efficiently common oseltamivir-resistant viruses, including those with the ubiquitous His274Tyr substitution[1].
Laninamivir (R 125489) is potent against p57N2, p09N1 and N5 with a similar binding mode to Zanamivir[1].
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