Indantadol (hydrochloride)


CAS No. : 202914-18-9

(Synonyms: CHF-3381)

202914-18-9
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Cat. No. : HY-101440A
M.Wt: 226.70
Formula: C11H15ClN2O
Purity: >98 %
Solubility:
Introduction of 202914-18-9 :

Indantadol hydrochloride (CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol hydrochloride blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol hydrochloride completely inhibits dopamine release caused by NMDA. Indantadol hydrochloride protects neurons, with an ED₅₀ of 35 μM. Indantadol hydrochloride has anticonvulsant and anti-high pain hypersensitivity activities[1][2][3].

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