Indantadol
CAS No. : 202844-10-8
(Synonyms: CHF-3381 (free base))
| Size | Price | Stock |
|---|---|---|
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| 500mg | $1048 | Get quote |
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| Cat. No. : | HY-101440 |
| M.Wt: | 190.24 |
| Formula: | C11H14N2O |
| Purity: | >98 % |
| Solubility: |
Indantadol (the free base of CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol completely inhibits dopamine release caused by NMDA. Indantadol protects neurons, with an ED₅₀ of 35 μM. Indantadol has anticonvulsant and anti-high pain hypersensitivity activities[1][2][3].
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