BMS-195270
CAS No. : 202822-23-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $175 | In-stock |
| 10mg | $280 | In-stock |
| 25mg | $560 | In-stock |
| 50mg | $900 | In-stock |
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| Cat. No. : | HY-120620 |
| M.Wt: | 355.70 |
| Formula: | C15H9ClF3N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
BMS-195270 is a small molecule that inhibits Carbachol (HY-B1208)-evoked tonicity of isolated rat bladder strips. BMS-195270 inhibits calcium flux[1].
In Vitro:BMS-195270 (3 μM) produces a dramatic reduction in developed pressure at infusion volumes of 0.2-1.3 mL and inhibits spontaneous contractions in an ex vivo rat whole bladder model[1].
BMS-195270 (2.8 mM) results adult worms of C. elegans displaying an Egl-d phenotype, as well as slowed or arrested pharyngeal pumping (Eat), and uncoordinated motion (Unc)[1].
BMS-195270 inhibits the response of HEK293 cells to the muscarinic agonist Carbachol (HY-B1208) with an EC50 of 2 μM[1].
BMS-195270 inhibits calcium flux, and retains inhibitory activity even when endogenous calcium channels are inactivated[1].
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