BMS-191011


CAS No. : 202821-81-6

(Synonyms: BMS-A)

202821-81-6
Price and Availability of CAS No. : 202821-81-6
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5mg $66 In-stock
10mg $99 In-stock
25mg $220 In-stock
50mg $370 In-stock
100mg $555 In-stock
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Cat. No. : HY-108593
M.Wt: 370.71
Formula: C16H10ClF3N2O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 202821-81-6 :

BMS 191011 (BMS-A) is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel). BMS-191011 shows neuroprotective activities in rodent models of stroke[1]. In Vitro:BMS-191011 (20 or 40 µM) activates BK channels in IGR39 cells, and leads to potentiation in Panc-1 cells[3]. In Vivo:BMS-191011 (intravenous injection; 10-100 µg/kg; once) dilates rat retinal arterioles through activation of iberiotoxin-sensitive BK(Ca) channels in vivo[2].

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