AHN 1-055 (hydrochloride)
CAS No. : 202646-03-5
(Synonyms: 3α-Bis-(4-fluorophenyl) Methoxytropane (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $90 | In-stock |
| 25mg | $170 | In-stock |
| 50mg | $260 | In-stock |
| 100mg | $400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101315 |
| M.Wt: | 379.87 |
| Formula: | C21H24ClF2NO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 33.33 mg/mL (ultrasonic) |
AHN 1-055 hydrochloride is a dopamine uptake inhibitor that can cross the blood-brain barrier, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT)[1].
IC50 & Target:IC50: 71 nM (dopamine uptake)[1]
In Vivo:AHN 1-055 (5 mg/kg; i.v.) inhibits the uptaking of brain dopamine with an IC50 of 311.8 ng/ml in vivo[1].
AHN 1-055 (10 mg/kg; i.v.) exhibits Cmax of 1.48 mg/L and terminal elimination half-lives of 7.69 h due to 1.8L/h/kg plasma clearance combined with 18.7 L/kg volumes of distribution[1].
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- Cat. No.:
- HY-101315
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