Thalidomide-O-amido-PEG-C2-NH2
CAS No. : 2022182-59-6
| Size | Price | Stock |
|---|---|---|
| 100mg | $300 | Get quote |
| 250mg | $498 | Get quote |
| 1g | $1402 | Get quote |
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| 10 g | Get quote | |
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| Cat. No. : | HY-122694 |
| M.Wt: | 418.40 |
| Formula: | C19H22N4O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Thalidomide-O-amido-PEG-C2-NH2 (Cereblon Ligand-Linker Conjugates 17), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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