Manitimus
CAS No. : 202057-76-9
(Synonyms: FK778)
| Size | Price | Stock |
|---|---|---|
| 1mg | $240 | In-stock |
| 5mg | $480 | In-stock |
| 10mg | $816 | In-stock |
| 20mg | $1440 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-101603 |
| M.Wt: | 308.26 |
| Formula: | C15H11F3N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Manitimus is an inhibitor of dehydroorotate dehydrogenase, and a potent immunosuppressive drug. In Vivo: In the Manitimus-treated rats, there is a dose-related, differential effect: mean survival is 15.7 days in group 4 (Manitimus 5 mg/kg), 19.1 days in group 5 (Manitimus 10 mg/kg) and 25.4 days in group 6 (Manitimus 20 mg/kg)[1]. Manitimus (15 mg/kg, p.o.) results in a significant decrease in neointimal area and percentage of stenosis versus the control rats, and diminishes the effect that CMV infection results in a significant increase in intimal and medial cross-sectional area and medial wall thickness of the vein grafts[2].
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