AZ1729
CAS No. : 2016864-46-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $312 | In-stock |
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| Cat. No. : | HY-121140 |
| M.Wt: | 369.42 |
| Formula: | C18H16FN5OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in Gi-mediated pathways, but not at those transduced by Gq/G11. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2[1]. IC50 & Target: FFA2[1]
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