Ac-DEVD-AFC
CAS No. : 201608-14-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $60 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $336 | In-stock |
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| Cat. No. : | HY-P1005 |
| M.Wt: | 729.61 |
| Formula: | C30H34F3N5O13 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL;DMSO : ≥ 50 mg/mL |
Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm). In Vitro: After incubation with Ac-DEVD-AFC for 1 hour, significant increase of caspase-3 activity is observed at 4 hour compare with control. There are no significant increases of caspase-3 activity in Photofrin and LPLI group. The cleavage of Ac-DEVD-AFC in response to caspase-3 activation is remarkably inhibited by shRNA-BimL transfection[1].
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