VU6004256
CAS No. : 2011034-33-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $310 | In-stock |
| 10mg | $500 | In-stock |
| 25mg | $1030 | In-stock |
| 50mg | $1650 | In-stock |
| 100mg | $2600 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-117408 |
| M.Wt: | 465.50 |
| Formula: | C25H25F2N5O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
VU6004256 is a potent and selective M1 muscarinic positive allosteric modulator (PAM) with an EC50 value of 155 nM. VU6004256 has the potential for the research of schizophrenia[1].
In Vivo: VU6004256 (10 mg/kg; i.p.) attenuates excessive pyramidal cell firing in the prefrontal cortex of NR1 KD mice[1].
VU6004256 (3, 10 mg/kg; i.p.) reverses the performance impairments in novel object recognition and cue-mediated fear conditioning tasks and reduces hyper locomotor activity in NR1 KD mice[1].
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