(S,R,S)-AHPC-PEG2-NH2
CAS No. : 2010159-60-9
(Synonyms: VH032-PEG2-NH2 ; VHL Ligand-Linker Conjugates 3 ; E3 ligase Ligand-Linker Conjugates 6 Free Base)
| Size | Price | Stock |
|---|---|---|
| 10mg | $70 | In-stock |
| 25mg | $140 | In-stock |
| 50mg | $220 | In-stock |
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| Cat. No. : | HY-103603A |
| M.Wt: | 575.72 |
| Formula: | C28H41N5O6S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1]. IC50 & Target: E3 Ligase Ligand-Linker Conjugate[1] In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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