(S,R,S)-AHPC-PEG2-N3
CAS No. : 2010159-45-0
(Synonyms: VH032-PEG2-N3; VHL Ligand-Linker Conjugates 6; E3 ligase Ligand-Linker Conjugates 13)
| Size | Price | Stock |
|---|---|---|
| 50mg | $171 | In-stock |
| 100mg | $302 | In-stock |
| 500mg | $1038 | In-stock |
| 1g | $1543 | In-stock |
| 2g | $3000 | Get quote |
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| Cat. No. : | HY-103599 |
| M.Wt: | 601.72 |
| Formula: | C28H39N7O6S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic);Ethanol : 50 mg/mL (ultrasonic) |
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-N3 can be used for the synthesis of PROTACs[1]. IC50 & Target:E3 Ligase Ligand-Linker Conjugate[1] In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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