GNE-6776
CAS No. : 2009273-71-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $220 | In-stock |
| 10mg | $350 | In-stock |
| 25mg | $700 | In-stock |
| 50mg | $1100 | In-stock |
| 100mg | $1800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-107986 |
| M.Wt: | 348.40 |
| Formula: | C20H20N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
GNE-6776 is a selective and orally bioavailable USP7 inhibitor[1]. IC50 & Target: USP7[1] In Vitro: GNE-6776 significantly inhibits USP7 at 15 µM. GNE-6776 is a highly selective USP7 inhibitor against both recombinant and endogenous cellular deubiquitinases[1]. In Vivo: GNE-6776 (100 or 200 mg/kg; oral gavage on a once or twice daily schedule; for 10 days) inhibits EOL-1 xenograft growth in mice[1].
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