Arformoterol (tartrate)


CAS No. : 200815-49-2

(Synonyms: (R,R)-Formoterol (tartrate))

200815-49-2
Price and Availability of CAS No. : 200815-49-2
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Cat. No. : HY-B0010D
M.Wt: 494.49
Formula: C23H30N2O10
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 200815-49-2 :

Arformoterol ((R,R)-Formoterol) tartrate, the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol tartrate can be used for the research of chronic obstructive pulmonary disease (COPD)[1][2]. In Vitro: Arformoterol tartrate induces cAMP accumulation in cultured human bronchial epithelial cells[1]. In Vivo: Arformoterol tartrate (10 ng in 0.1 ml saline/20 g body weight; intranasal instillation) mitigates Cl2-induced increases of respiratory system resistance and elastance in mice[3].
Arformoterol tartrate reverses histamine- and ovalbumin-induced bronchoconstriction in guinea pigs (ED50s=1 and 40 nmol/kg, respectively)[1].

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