PD1-PDL1-IN 1
CAS No. : 2005454-12-4
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| Cat. No. : | HY-101058 |
| M.Wt: | 385.38 |
| Formula: | C14H23N7O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1]. In Vitro:PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].
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