Omigapil (maleate)
CAS No. : 200189-97-5
(Synonyms: CGP3466B; CGP3446 (maleate); TCH346 (maleate))
| Size | Price | Stock |
|---|---|---|
| 5mg | $88 | In-stock |
| 10mg | $143 | In-stock |
| 25mg | $275 | In-stock |
| 50mg | $440 | In-stock |
| 100mg | $715 | In-stock |
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| Cat. No. : | HY-16361A |
| M.Wt: | 391.42 |
| Formula: | C23H21NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C) |
Omigapil maleate (CGP3466B), an orally active GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD). Omigapil maleate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1][2]. IC50 & Target:Apoptosis[2] In Vivo:Treatment of mice with Omigapil (0.1 mg/kg) results in improved muscle regeneration and increased force[2].
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