INH14
CAS No. : 200134-22-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $120 | In-stock |
| 50mg | $190 | In-stock |
| 100mg | $300 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-114454 |
| M.Wt: | 240.30 |
| Formula: | C15H16N2O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity[1]. IC50 & Target: IC50: 8.97 μM (IKKα), 3.59 μM (IKKβ)[1] In Vivo: INH14 (5 µg/g, i.p. for 2 hours) reduces lipopeptide-induced inflammation in mice[1].
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