SJ572403
CAS No. : 19970-45-7
(Synonyms: SJ403)
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $155 | In-stock |
| 25mg | $310 | In-stock |
| 50mg | $495 | In-stock |
| 100mg | $720 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-114712 |
| M.Wt: | 275.31 |
| Formula: | C13H17N5O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 13.89 mg/mL (ultrasonic) |
SJ572403 (SJ403) is a p27Kip1 inhibitor. SJ572403 has high specificity for specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM. SJ572403 can be used for the research of diseases associated with intrinsically disordered proteins (IDPs)[1].
IC50 & Target:Kd: 2.2 mM (p27-KID)[1]
In Vitro:SJ572403 (SJ403) (3 mM) shows specific interactions with specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM[1].
SJ572403 (0-3 mM) modulates p27's Cdk regulatory[1].
SJ572403 (10 μM-3 mM) displaces p27-D2 from Cdk2/cyclin A and partially restores Cdk2 kinase activity[1].
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