Etiprednol dicloacetate


CAS No. : 199331-40-3

(Synonyms: BNP 166; Etiprednol dichloroacetate)

199331-40-3
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Cat. No. : HY-106215
M.Wt: 485.40
Formula: C24H30Cl2O6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 199331-40-3 :

Etiprednol dicloacetate (BNP 166) is an anti-inflammatory agent. Etiprednol dicloacetate inhibits eosinophil accumulation. Etiprednol dicloacetate can be used in the research of inflammatory airway diseases, such as asthma[1][2]. In Vitro:Etiprednol dicloacetate (1 nM-1 μM) inhibits LPS-induced TNF-α production by human blood[1].
In Vivo:Etiprednol dicloacetate (0-100 μg/kg, intranasal inhalation) attenuates peribronchial eosinophilia in the lung of the allergen sensitized and challenged rats[1].
Etiprednol dicloacetate (0.1 μg/kg, intranasal inhalation) inhibits eosinophil accumulation in rats (antigen-induced airway eosinophil infiltration)[3].
Etiprednol dicloacetate (0-20 mg/kg, p.o., 28 days) is well tolerated in rats and dogs[2].

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