Bavachinin
CAS No. : 19879-30-2
(Synonyms: 7-O-Methylbavachin; Bavachinin A)
| Size | Price | Stock |
|---|---|---|
| 5mg | $79 | In-stock |
| 10mg | $106 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $384 | In-stock |
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| Cat. No. : | HY-N0234 |
| M.Wt: | 338.40 |
| Formula: | C21H22O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5].
In Vitro:Bavachinin (25，50 μM; 24 h) increases PPARγ protein expression[4].
In Vivo:Bavachinin (5 mg/kg; i.p.; four consecutive weeks) suppresses tumor growth and angiogenesis in Athymic nude mice bearing KB tumor[2].
Bavachinin (50 mg/kg; p.o.; seven consecutive days) has therapeutic effect on asthma mice [3].
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