Nicotinamide N-oxide


CAS No. : 1986-81-8

1986-81-8
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Cat. No. : HY-101407
M.Wt: 138.13
Formula: C6H6N2O2
Purity: >98 %
Solubility: DMSO : 5.83 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 20 mg/mL (ultrasonic)
Introduction of 1986-81-8 :

Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. In Vitro:Nicotinamide is one of the forms of vitamin B3. It is a precursor for nicotinamide adenine dinucleotide, which is best known as an electron carrier in oxidative phosphorylation and as a cofactor for many dehydrogenases. It is metabolized through two enzymatic systems. The first system starts with the methylation of nicotinamide by nicotinamide N-methyltransferase, which can subsequently be oxidized by aldehyde oxidase. The second enzymatic system oxidizes nicotinamide to Nicotinamide N-oxide[1].

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