Anticancer agent 253


CAS No. : 1983924-33-9

1983924-33-9
Price and Availability of CAS No. : 1983924-33-9
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Cat. No. : HY-116904
M.Wt: 500.51
Formula: C29H23F3N4O
Purity: >98 %
Solubility:
Introduction of 1983924-33-9 :

Anticancer agent 253 (Compound 26) has anti-cancer activity against breast cancer cells, with IC50s of 6 μM (MCF-7), 10 μM (MDA-MB-231) and 6.4 μM (4T1 cells). Anticancer agent 253 arrests cell cycle and induces mitochondria-mediated apoptosis in cancer cells. Anticancer agent 253 inhibits Akt phosphorylation in human breast and prostate cancer[1].

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