VK4-116
CAS No. : 1982347-43-2
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| Cat. No. : | HY-123889 |
| M.Wt: | 485.02 |
| Formula: | C26H33ClN4O3 |
| Purity: | >98 % |
| Solubility: |
VK4-116 (Compound 19) is a selective Dopamine D3 receptor (D3R) antagonist with a Ki of 6.84 nM.VK4-116 significantly inhibits Oxycodone-induced hyperlocomotion and locomotor sensitization in mouse models. VK4-116 with pretreatment also inhibits the acquisition of Oxycodone-induced conditioned place preference (CPP) in rat models[1].
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