Methdilazine
CAS No. : 1982-37-2
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| Cat. No. : | HY-B1690 |
| M.Wt: | 296.43 |
| Formula: | C18H20N2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Methdilazine is an orally active antibiotic (histamine antagonist). Methdilazine can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2]. IC50 & Target: MIC: 5-15 μg/mL (mycobacterium) In Vitro: Methdilazine (0-20 μg/mL approximately, 18 h) inhibits kinds of mycobacterium with MIC values ranging from 5 μg/mL to 15 μg/mL[1]. In Vivo: Methdilazine (Intraperitoneal injection, 10 μg/gm body wt/day, 6 weeks) is antagonistic to mycobacteria in H37Rv infected mice[1]. Methdilazine (Oral administration, 10 mg/kg per day, 28 days) improves survival of Mycobacterium Tuberculosis (Mtb) H37Rv infected mice[2].
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