Uridine triphosphate (trisodium salt)
CAS No. : 19817-92-6
(Synonyms: UTP trisodium salt; Uridine 5'-triphosphate trisodium salt)
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| Cat. No. : | HY-W013093 |
| M.Wt: | 550.09 |
| Formula: | C9H12N2Na3O15P3 |
| Purity: | >98 % |
| Solubility: | H2O : 75 mg/mL (ultrasonic);DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C) |
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors[1][2].
In Vitro:Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 µM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through activation of P2Y2 receptors and through the increase of extracellular MMP-2 activation and expression[2].
Uridine triphosphate (UTP) trisodium salt evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment, and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h[2].
In Vivo:Uridine triphosphate (UTP) (0.44-4.4 µg/kg; i.v.; once) trisodium salt reduces infarct size and improves rat heart function after myocardial infarct[3].
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