| Size | Price | Stock |
|---|---|---|
| 500mg | $55 | In-stock |
| 5g | $66 | In-stock |
| 10g | $105 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13679 |
| M.Wt: | 164.18 |
| Formula: | C2H5NaO3S2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL;DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C) |
Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide[1][2].
In Vitro: Mesna (1-1000 μM) reduces H2O2, HOCl and OH concentrations in a dose-dependent manner, with an IC50 of 32, 21, and 305 μM, respectively in cell-free experiments[3].
In Vivo: Mesna (150 mg/kg; a single i.p.) protects the rat brain against traumatic injury[1].
Mesna (200 mg/kg; a single i.p.) attenuates the cisplatin-induced ovarian damages in rats[2].
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