Sodium 2-mercaptoethanesulfonate


CAS No. : 19767-45-4

(Synonyms: Mesnum)

19767-45-4
Price and Availability of CAS No. : 19767-45-4
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500mg $55 In-stock
5g $66 In-stock
10g $105 In-stock
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Cat. No. : HY-13679
M.Wt: 164.18
Formula: C2H5NaO3S2
Purity: >98 %
Solubility: H2O : ≥ 50 mg/mL;DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 19767-45-4 :

Mesna (Sodium 2-mercaptoethanesulfonate) is an antioxidant which has cytoprotective effects. Mesna is widely used as a systemic protective agent against chemotherapy toxicity. Mesna is also used to reduce hemorrhagic cystitis induced by cyclophosphamide[1][2]. In Vitro: Mesna (1-1000 μM) reduces H2O2, HOCl and OH concentrations in a dose-dependent manner, with an IC50 of 32, 21, and 305 μM, respectively in cell-free experiments[3]. In Vivo: Mesna (150 mg/kg; a single i.p.) protects the rat brain against traumatic injury[1].
Mesna (200 mg/kg; a single i.p.) attenuates the cisplatin-induced ovarian damages in rats[2].

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