Valiglurax


CAS No. : 1976050-09-5

(Synonyms: VU0652957; VU2957)

1976050-09-5
Price and Availability of CAS No. : 1976050-09-5
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5mg $90 In-stock
10mg $150 In-stock
25mg $320 In-stock
50mg $545 In-stock
100mg $920 In-stock
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Cat. No. : HY-122647
M.Wt: 329.28
Formula: C16H10F3N5
Purity: >98 %
Solubility: DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1976050-09-5 :

Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease[1]. In Vivo:Valiglurax (VU0652957; 0.3-30 mg/kg; po) reverses haloperidol (HY-14538)-induced catalepsy (HIC) in rats in a dose-dependent manner[1].

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