Pramlintide (acetate hydrate)
CAS No. : 196078-30-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $168 | In-stock |
| 25mg | $360 | Get quote |
| 50mg | $520 | Get quote |
| 100mg | $715 | Get quote |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-109552 |
| M.Wt: | 1000.00 |
| Formula: | C171H267N51O53S2·xC2H4O2.xH2O |
| Purity: | >98 % |
| Solubility: |
Pramlintide acetate hydrate is a polypeptide analogue of human amylin. Pramlintide acetate hydrate, an antidiabetic agent, is antineoplastic in colorectal cancer[1].
In Vitro:Pramlintide inhibits the growth of HCT-116 and HT-29 in a dose-dependent manner, with higher efficacy against the latter (IC50s of 48.67 and 9.10 μg/mL, respectively)[1].
The addition of 5, 10, and 20 μg/mL of Pramlintide to HCT-116 and HT-29 with 5-fluorouracil, Oxaliplatin, or Irinotecan induces the antiproliferative effect synergistically[1].
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