Corifollitropin alfa


CAS No. : 195962-23-3

(Synonyms: Org 36286; MK-8962)

195962-23-3
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Cat. No. : HY-118860
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 195962-23-3 :

Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility[1][2][3]. IC50 & Target:FSH Receptor[2] In Vivo: Corifollitropin alfa (20 μg/kg, s.c., single injection) shows a t1/2 of 17.3 h and Cmax of 3.2 ng/mL/μg/kg in female Wistar rats[2].
Corifollitropin alfa (2.5-40 μg/kg, s.c.) stimulates superovulation in rats[2].
Corifollitropin alfa (3 μg, supplemented with hCG, s.c.) increases ovulation rate and recovered embryos in rabbits[3].

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